1,419 research outputs found

    Decay Constants of Pseudoscalar DD-mesons in Lattice QCD with Domain-Wall Fermion

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    We present the first study of the masses and decay constants of the pseudoscalar D D mesons in two flavors lattice QCD with domain-wall fermion. The gauge ensembles are generated on the 243×4824^3 \times 48 lattice with the extent Ns=16 N_s = 16 in the fifth dimension, and the plaquette gauge action at β=6.10 \beta = 6.10 , for three sea-quark masses with corresponding pion masses in the range 260475260-475 MeV. We compute the point-to-point quark propagators, and measure the time-correlation functions of the pseudoscalar and vector mesons. The inverse lattice spacing is determined by the Wilson flow, while the strange and the charm quark masses by the masses of the vector mesons ϕ(1020) \phi(1020) and J/ψ(3097) J/\psi(3097) respectively. Using heavy meson chiral perturbation theory (HMChPT) to extrapolate to the physical pion mass, we obtain fD=202.3(2.2)(2.6) f_D = 202.3(2.2)(2.6) MeV and fDs=258.7(1.1)(2.9) f_{D_s} = 258.7(1.1)(2.9) MeV.Comment: 15 pages, 3 figures. v2: the statistics of ensemble (A) with m_sea = 0.005 has been increased, more details on the systematic error, to appear in Phys. Lett.

    DNA Ligase I Is Not Essential for Mammalian Cell Viability

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    SummaryOf the three DNA ligases present in all vertebrates, DNA ligase I (Lig1) has been considered essential for ligating Okazaki fragments during DNA replication and thereby essential for cell viability. Here, we report the striking finding that a Lig1-null murine B cell line is viable. Surprisingly, the Lig1-null cells exhibit normal proliferation and normal immunoglobulin heavy chain class switch recombination and are not hypersensitive to a wide variety of DNA damaging agents. These findings demonstrate that Lig1 is not absolutely required for cellular DNA replication and repair and that either Lig3 or Lig4 can substitute for the role of Lig1 in joining Okazaki fragments. The establishment of a Lig1-null cell line will greatly facilitate the characterization of DNA ligase function in mammalian cells, but the finding alone profoundly reprioritizes the role of ligase I in DNA replication, repair, and recombination

    Topological susceptibility in finite temperature QCD with physical (u/d,s,c)(u/d, s, c) domain-wall quarks

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    We perform hybrid Monte-Carlo (HMC) simulation of lattice QCD with Nf=2+1+1N_f=2+1+1 domain-wall quarks at the physical point, on the 643×(64,20,16,12,10,8,6)64^3 \times (64,20,16,12,10,8,6) lattices, each with three lattice spacings. The lattice spacings and the bare quark masses are determined on the 64464^4 lattices. The resulting gauge ensembles provide a basis for studying finite temperature QCD with Nf=2+1+1N_f=2+1+1 domain-wall quarks at the physical point. In this paper, we determine the topological susceptibility of the QCD vacuum for T>Tc150T > T_c \sim 150 MeV. The topological charge of each gauge configuration is measured by the clover charge in the Wilson flow at the same flow time in physical units, and the topological susceptibility χt(a,T) \chi_t(a,T) is determined for each ensemble with lattice spacing aa and temperature TT. Using the topological susceptibility χt(a,T)\chi_t(a,T) of 15 gauge ensembles with three lattice spacings and different temperatures in the range T155516T \sim 155-516 MeV, we extract the topological susceptibility χt(T)\chi_t(T) in the continuum limit. Moreover, a detailed discussion on the reweighting method for domain-wall fermion is presented.Comment: 36 pages, 5 figure
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